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Expert Content LibraryIntro To BFS

Chapter 14: Transportation

Blow-Fill-Seal provides several transportation advantages over traditional glass vials.

First, filled BFS containers are more resistant to breakage than glass vials at non-frozen temperatures. This is because a BFS container is made of plastic resin, not glass, which is inherently brittle.

Second, since BFS containers are made from pharmaceutical-grade resin, they do not run the risk of having glass flakes enter the drug product during transportation.

BFS containers also weigh less than unit-dose glass vials and do not have additional components such as plungers, stoppers or crimps that need to be transported in for assembly.

And lastly, unit-dose BFS containers can be packaged as efficiently in the cold chain as unit-dose glass vials or prefilled syringes.

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